optimized planning of thermo-ablation procedures

Scientific Context

In our research team MIMESIS, we develop interactive simulations targetting the training of medical students, pre-operative planning or per-operative guidance for surgeons. These simulations model the physiological behavior of the human body.

Within our partnership with the IHU Strasbourg (www.ihu-strasbourg.eu), we develop innovative tools for interventional radiologists. The interventional radiology is the medical field treating diseases using different type of imaging (Xray, MRI…). We are more precisely focusing on the cryoablation and radio-frequency (RF) procedure. For cryoablation, the surgical technique consists in inserting several cryo-needles inside the tumor, decompressing a gaz (argon) to freeze the tumor untill cellular death (apoptosis). When the tumor is large, several needles must be used but the planning of the procedure requires a lot of experience. For RF ablation, the needles used differ since an electrical current is used to heat the tissue, thus leading to cellular death.

We therefore develop a planification tool to better anticipate the effect of any thermal ablation before the operation. This represents a real challenge and would greatly help surgeons and interventional radiologists.

Objectives

The objectives of the internships are:

  • Optimization of the thermal simulation using new solvers and numerical methods
  • Development of an interative tool allowing to optimize the placement of needles in a 3D environment
  • Labelization/segmentation of the blood vessels in CT scans. Tools are already available in our simulation platform SOFA
  • A part of the internship will involve experiments in order to compare results with experimental data

This PhD would be located in Strasbourg, at IHU Strasbourg.

Required Skills

Most of all, motivation is needed !!!

Knowledge in optimization methods, numerical methods and thermal equations.

Knowledge in C++, python.

Contacts

Hugo Talbot

Hugo Talbot

Sofa Consortium Coordinator

Stéphane Cotin

Research Director